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The impact of rehabilitation-oriented virtual reality device in patients with ischemic stroke in the early subacute recovery phase: Study protocol for a phase III, single-blinded, randomized, controlled clinical trial

Ahmed, Nima and Mauad, Vitor A. Queiroz and Gomez-Rojas, Olga and Sushea, Ammu and Castro-Tejada, Gelanys and Michel, Janet and Liñares, Juan Manuel and Pedrosa Salles, Loise and Candido Santos, Ludmilla and Shan, Ming and Nassir, Rami and Montañez-Valverde, Raul and Fabiano, Ronaldo and Danyi, Sofia and Hassan Hosseyni, Seyed and Anand, Seerat and Ahmad, Usman and Casteleins, William Augusto and Sanchez, Alma Tamara and Fouad, Ahmed and Jacome, Alvaro and Moura de Oliveira Paiva, Mariana Sanali and Saavedra Ruiz, Ana Gabriela and Grochowski, Rubens A. and Toyama, Mayumi and Nagi, Hibatalla and Sarvodelli, Marcella Zanini and Halalau, Alexandra. (2020) The impact of rehabilitation-oriented virtual reality device in patients with ischemic stroke in the early subacute recovery phase: Study protocol for a phase III, single-blinded, randomized, controlled clinical trial. Journal of central nervous system disease, 12. p. 1179573519899471.

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Official URL: https://edoc.unibas.ch/75591/

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Abstract

Stroke is considered the most common cause of adult disability. Intensive rehabilitation protocols outperform nonintensive counterparts. The subacute stroke phase represents a potential window to recovery. Virtual reality (VR) has been shown to provide a more stimulating environment, allowing for increased patient compliance. However, the quality of current literature comparing VR with standard therapies is limited. Our aim is to measure the impact of VR versus standard therapy on the recovery of the upper limb motor function in patients with stroke in the early subacute recovery phase.; This is a randomized, controlled trial that will assign 262 patients to tailor-made standard rehabilitation (TMSR) or TMSR plus immersive VR device. The trial will be conducted in an urban rehabilitation clinic in the United States with expertise in the management of poststroke patients. Patients will be 18 to 70 years of age and in the early subacute period (30-90 days post ischemic stroke). The primary outcome will be the change of Fugl-Meyer Assessment-Upper Extremity (FMA-UE) score, measured at baseline and 13 weeks after randomization. The secondary outcome will be the change in the UK Functional Independence Measure and Functional Assessment Measure (UK FIM-FAM) score at the same time points.; If the use of VR in the rehabilitation of patients with stroke proves to have a significant impact on their motor recovery, it will constitute an extremely important step into decreasing the functional impairment associated with stroke and the related health care expense burden.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Household Economics and Health Systems Research > Household Economy (Fink)
UniBasel Contributors:Michel, Janet
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Sage Publications
ISSN:1179-5735
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:05 Mar 2020 09:45
Deposited On:05 Mar 2020 09:45

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