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Leprosy post-exposure prophylaxis with single-dose rifampicin: toolkit for implementation

Barth-Jaeggi , T. and Cavaliero, A. and Aerts, A. and Anand, S. and Arif, M. and Sarady Ay , S. and Maung Aye , T. and Banstola, N. L. and Baskota, R. and Blaney, D. and Bonenberger, M. and van Brakel , W. and Cross, H. and Das, V. K. and Budiawan, T. and Fernando, N. and Gani, Z. and Greter, H. and Ignotti, E. and Kamara, D. and Kasang, C. and Kömm, B. and Kumar, A. and Lay, S. and Mieras, L. and Mirza, F. and Mutayoba, B. and Njako, B. and Pakasi, T. and Richardus, J. H. and Saunderson, P. and Smith, C. S. and Stäheli, R. and Suriyarachchi, N. and Shwe, T. and Tiwari, A. and Supun, M. and Wijesinghe, D. and van Berkel , J. and Vander Plaetse , B. and Virmond, M. and Steinmann, P.. (2019) Leprosy post-exposure prophylaxis with single-dose rifampicin: toolkit for implementation. Leprosy review, 90. pp. 356-363.

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Official URL: https://edoc.unibas.ch/75039/

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Abstract

lNLR, Amsterdam, NetherlandsmPrivate, UKnHealth Services, Dadra and Nagar Haveli, IndiaoNLR, Jakarta, IndonesiapAnti-Leprosy Campaign, Colombo, Sri LankaqUniversidade do Estado de Mato Grosso, Ca ́ceres, BrazilrNational Tuberculosis and Leprosy Programme, Dar es Salaam,TanzaniasGerman Leprosy and Tuberculosis Relief Association, Wu ̈rzburg,GermanytDirectorate General of Health Services, MoHFW, New Delhi, IndiauNational Leprosy Elimination Program, Phnom Penh, CambodiavGerman Leprosy and Tuberculosis Relief Association,Dar es Salaam, TanzaniawSub Directorate Directly Transmitted Tropical Diseases, MoH,Jakarta, IndonesiaxErasmus MC, University Medical Center Rotterdam, Rotterdam,NetherlandsyAmerican Leprosy Missions, Greenville, USAzUniversity of Aberdeen, Aberdeen, UKaaFAIRMED, Colombo, Sri LankaabInstituto Lauro de Souza Lima, Bauru, BrazilAccepted for publication 22 July 2019SummaryObjective:Leprosy post-exposure prophylaxis with single-dose rifampicin (SDR-PEP) has proven effective and feasible, and is recommended by WHO since 2018.This SDR-PEP toolkit was developed through the experience of the leprosy post-exposure prophylaxis (LPEP) programme. It has been designed to facilitate andstandardise the implementation of contact tracing and SDR-PEP administration inregions and countries that start the intervention.Results:Four tools were developed, incorporating the current evidence for SDR-PEP and the methods and learnings from the LPEP project in eight countries. (1) theSDR-PEP policy/advocacy PowerPoint slide deck which will help to inform policymakers about the evidence, practicalities and resources needed for SDR-PEP, (2) theSDR-PEP field implementation training PowerPoint slide deck to be used to trainfront line staff to implement contact tracing and PEP with SDR, (3) the SDR-PEPgeneric field guide which can be used as a basis to create a location specific fieldprotocol for contact tracing and SDR-PEP serving as a reference for frontline fieldstaff. Finally, (4) the SDR-PEP toolkit guide, summarising the different componentsof the toolkit and providing instructions on its optimal use.Conclusion:In response to interest expressed by countries to implement contacttracing and leprosy PEP with SDR in the light of the WHO recommendation of SDR-PEP, this evidence-based, concrete yet flexible toolkit has been designed to servenational leprosy programme managers and support them with the practical means toLeprosy post-exposure prophylaxis toolkit357 translate policy into practice. The toolkit is freely accessible on the Infolep homepagesand updated as required: https://www.leprosy-information.org/keytopic/leprosy-post-exposure-prophylaxis-lpep-programme
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Swiss Centre for International Health (SCIH) > Health Systems Support (Prytherch)
UniBasel Contributors:Barth-Jaeggi, Tanja and Greter, Helena and Steinmann, Peter
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:LEPRA Health in Action
ISSN:0024-1032
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:05 Mar 2020 08:02
Deposited On:05 Mar 2020 08:02

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