A RCT evaluating a pragmatic in-hospital service to increase the quality of discharge prescriptions

Brühwiler, Lea D. and Beeler, Patrick E. and Böni, Fabienne and Giger, Rebekka and Wiedemeier, Peter G. and Hersberger, Kurt E. and Lutters, Monika. (2019) A RCT evaluating a pragmatic in-hospital service to increase the quality of discharge prescriptions. International Journal for Quality in Health Care, 31 (8). G74-G80.

Full text not available from this repository.

Official URL: https://edoc.unibas.ch/74583/

Downloads: Statistics Overview


To improve discharge prescription quality and information transfer to improve post-hospital care with a pragmatic in-hospital service.; A single-centre, randomized controlled trial.; Internal medicine wards in a Swiss teaching hospital.; Adult patients discharged to their homes, 76 each in the intervention and control group.; Medication reconciliation at discharge by a clinical pharmacist, a prescription check for formal flaws, interactions and missing therapy durations. Important information was annotated on the prescription.; At the time of medication dispensing, community pharmacy documented their pharmaceutical interventions when filling the prescription. A Poisson regression model was used to compare the number of interventions (primary outcome). The significance of the pharmaceutical interventions was categorized by the study team. Comparative analysis was used for the significance of interventions (secondary outcome).; The community pharmacy staff performed 183 interventions in the control group, and 169 in the intervention group. The regression model revealed a relative risk for an intervention of 0.78 (95% CI 0.62-0.99, p = 0.04) in the intervention group. The rate of clinically significant interventions was lower in the intervention group than in the control group (72 of 169 (42%) vs. 108 of 183 (59%), p < 0.01), but more economically significant interventions were performed (98, 58% vs. 80, 44%, p < 0.01).; The pragmatic in-hospital service increased the quality of prescriptions. The intervention group had a lower risk for the need for pharmaceutical interventions, and clinically significant interventions were less frequent. Overall, our pragmatic approach showed promising results to optimize post-discharge care.
Faculties and Departments:05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Ehemalige Einheiten Pharmazie > Pharmaceutical Care (Hersberger)
UniBasel Contributors:Hersberger, Kurt E. and Böni, Fabienne
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Oxford University Press
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:14 Apr 2021 08:00
Deposited On:21 Jan 2020 09:40

Repository Staff Only: item control page