Scalable Synthesis of Acridinium Catalysts for Photoredox Deuterations

Zilate, Bouthayna and Fischer, Christian and Schneider, Lukas and Sparr, Christof. (2019) Scalable Synthesis of Acridinium Catalysts for Photoredox Deuterations. Synthesis, 51 (23). pp. 4359-4365.

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Official URL: https://edoc.unibas.ch/74208/

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The continuous development of photocatalytic methods incentivizes the design of organic catalysts to complement the frequently used and precious polypyridyl transition metal systems. Herein, a scalable synthesis of suitable acridinium dyes and their application in photoredox deuterations are described. The acridinium catalysts, prepared on multi-gram scale, allowed the deuteration of a pharmaceutically relevant scaffold in high yield and selectivity under mild conditions.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Organische Chemie (Sparr)
UniBasel Contributors:Sparr, Christof and Schneider, Lukas and Fischer, Christian and Zilate, Bouthayna
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Georg Thieme
Note:Publication type according to Uni Basel Research Database: Journal article
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edoc DOI:
Last Modified:01 Dec 2020 02:30
Deposited On:21 Jan 2020 14:15

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