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Clinical course of neuropathologically confirmed frontal-variant Alzheimer's disease

Taylor, Kirsten I. and Probst, Alphonse and Miserez, André R. and Monsch, Andreas U. and Tolnay, Markus. (2008) Clinical course of neuropathologically confirmed frontal-variant Alzheimer's disease. Nature clinical practice. Neurology, Vol. 4, no. 4. pp. 226-232.

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Official URL: http://edoc.unibas.ch/dok/A5250774

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Abstract

Background: A 66-year-old man presented with a 3-year history of personality changes marked by increasing apathy, social withdrawal and deficits in complex attention, and a 1-year history of progressive memory problems and difficulties in planning and carrying out complex tasks. Investigations: Three neuropsychological examinations over 2 years, neurological examination, routine laboratory tests, brain MRI, single-photon emission CT scan, genetic analyses, and neuropathological examination. Diagnosis: A clinical diagnosis of frontal-variant frontotemporal dementia was superseded by postmortem neuropathological evidence, which established a diagnosis of frontal-variant Alzheimer's disease. Management: The patient and his spouse were referred for counseling, and the patient was referred for follow-up examinations.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB > Allgemeine Pathologie (Tolnay)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB > Allgemeine Pathologie (Tolnay)
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Geriatrie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Geriatrie
07 Faculty of Psychology > Departement Psychologie
UniBasel Contributors:Monsch, Andreas U and Tolnay, Markus and Miserez, Andre Roger and Taylor, Kirsten and Probst, Alphonse
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Bibsysno:Link to catalogue
Publisher:Nature Publishing Group
ISSN:1745-834X
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:05 Dec 2014 09:45
Deposited On:22 Mar 2012 13:39

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