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Suitability of a propanolic PVP-iodophor preparation as preoperative skin disinfectant: germicidal activity and chemical stability

Grünig, H. M. and Mühlebach, S.. (1988) Suitability of a propanolic PVP-iodophor preparation as preoperative skin disinfectant: germicidal activity and chemical stability. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Serie B,, 186 (4). pp. 360-367.

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Official URL: https://edoc.unibas.ch/72519/

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Abstract

The preparation Solutio Betadini propanolica 3% w/w, used as a pre-operative skin disinfectant was examined for its germicidal activity and its chemical stability. The additive activity of iodine and propanol resulted in a wide range of antimicrobial activity against bacteria, including bacterial spores, and fungi, with a rapid onset and sustained duration of action. The solution is easily manufactured and analyzed, its stability is guaranteed for 6 months. Because of its staining property, there is no need of coloured additives to mark the disinfected area. In addition, no skin irritations by the disinfectant were observed so far. Thus, the preparation fulfills the essential requirements for preoperative skin disinfectants and is suitable for the preparation and the compounding in hospital pharmacies.
Faculties and Departments:05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Klinische Pharmazie/Spitalpharmazie (Meier)
UniBasel Contributors:Mühlebach, Stefan F
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:0932-6073
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:06 Nov 2020 16:07
Deposited On:06 Nov 2020 16:07

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