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P4T-DOTA - a lanthanide chelating tag combining a sterically highly overcrowded backbone with a reductively stable linker

Joss, Daniel and Haussinger, Daniel. (2019) P4T-DOTA - a lanthanide chelating tag combining a sterically highly overcrowded backbone with a reductively stable linker. Chemical Communications , 55 (71). pp. 10543-10546.

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Abstract

Herein we report a DOTA-based lanthanide chelating tag (LCT) with rigidified backbone and a reduction-stable linker. The newly developed tag induces strong pseudocontact shifts suitable for paramagnetic protein nuclear magnetic resonance spectroscopy and the obtained anisotropic susceptibility parameters are in the range of the best performing LCTs.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Nuclear Magnetic Resonance (Häussinger)
UniBasel Contributors:Joss, Daniel and Häussinger, Daniel
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Royal Society of Chemistry
ISSN:1359-7345
e-ISSN:1364-548X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
edoc DOI:
Last Modified:23 Oct 2019 07:52
Deposited On:23 Oct 2019 07:52

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