En route to terpene natural products utilizing supramolecular cyclase mimetics

Zhang, Qi and Catti, Lorenzo and Syntrivanis, Leonidas-Dimitrios and Tiefenbacher, Konrad. (2019) En route to terpene natural products utilizing supramolecular cyclase mimetics. Natural Product Reports. Epub.

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Official URL: https://edoc.unibas.ch/72303/

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Covering: literature up to 2018Terpenes are a class of natural products characterized by remarkable structural diversity. Much of this diversity arises biosynthetically from a handful of linear precursors through the so-called tail-to-head terpene cyclization reaction. This reaction is one of the most complex observed in nature, and historically attempts to replicate it with non-enzymatic means have met with little success. In recent years, however, the development of manmade binding pockets that allow such reactions to take place has been reported. This Highlight provides an overview of this nascent field, and outlines the challenges that need to be overcome moving forward.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Synthesis of Functional Modules (Tiefenbacher)
UniBasel Contributors:Tiefenbacher, Konrad Karl
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:The Royal Society of Chemistry
Note:Publication type according to Uni Basel Research Database: Journal article
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edoc DOI:
Last Modified:23 Oct 2019 07:47
Deposited On:23 Oct 2019 07:47

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