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Anatomical and functional outcome in brilliant blue G assisted chromovitrectomy

Henrich, Paul B. and Haritoglou, Christos and Meyer, Peter and Ferreira, Paulo R. and Schötzau, Andreas and Katamay, Robert and Josifova, Tatjana and Schneider, Ulrike and Flammer, Josef and Priglinger, Siegfried. (2010) Anatomical and functional outcome in brilliant blue G assisted chromovitrectomy. Acta ophthalmologica, Vol. 88, H. 5. pp. 588-593.

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Official URL: http://edoc.unibas.ch/dok/A5252350

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Abstract

Purpose: To evaluate the potential of brilliant blue G (BBG) for intraoperative staining of the inner limiting membrane (ILM) with respect to staining properties and surgical outcome. Methods: In a retrospective, non-comparative clinical case series, we analysed 17 consecutive chromovitrectomy interventions for surgery of macular holes, ERMs, vitreoretinal traction syndromes and cystoid macular oedema. Following complete posterior vitreous detachment, BBG was injected into the vitreous cavity at a concentration of 0.25 mg/ml, followed by immediate washout. Main outcome measures were staining properties, visual acuity, central visual field testing and optical coherence tomography (OCT) measurements over a mean follow-up period of 3 months. Results: ILM staining was somewhat less intensive for BBG than for average indocyanine green (ICG) chromovitrectomy. However, the ILM was removed successfully without additional ICG in 15/17 patients. Postoperative visual acuity was improved in 16/17 patients and remained unchanged in one patient. Central retinal OCT thickness showed a postoperative reduction, with values ranging from +7 to -295 mum (median -89 mum). Neither visual field defects nor any other adverse events were recorded. Conclusion: BBG permits sufficient staining for safe ILM removal. In this short-term study, good anatomical and functional results were achieved and no adverse events were observed.
Faculties and Departments:03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Ehemalige Einheiten Spezialfächer (Klinik) > Ophthalmologie (Flammer)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Ehemalige Einheiten Spezialfächer (Klinik) > Ophthalmologie (Flammer)
03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Ocular Pharmacology and Physiology (Neutzner/Meyer)
UniBasel Contributors:Flammer, Josef and Meyer, Peter
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Wiley-Blackwell
ISSN:0001-639X
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:19 Jul 2013 07:37
Deposited On:22 Mar 2012 13:38

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