Ambient particulate air pollution and daily mortality in 652 cities

Liu, Cong and Chen, Renjie and Sera, Francesco and Vicedo-Cabrera, Ana M. and Guo, Yuming and Tong, Shilu and Coelho, Micheline S. Z. S. and Saldiva, Paulo H. N. and Lavigne, Eric and Matus, Patricia and Valdes Ortega, Nicolas and Osorio Garcia, Samuel and Pascal, Mathilde and Stafoggia, Massimo and Scortichini, Matteo and Hashizume, Masahiro and Honda, Yasushi and Hurtado-Díaz, Magali and Cruz, Julio and Nunes, Baltazar and Teixeira, João P. and Kim, Ho and Tobias, Aurelio and Íñiguez, Carmen and Forsberg, Bertil and Åström, Christofer and Ragettli, Martina S. and Guo, Yue-Leon and Chen, Bing-Yu and Bell, Michelle L. and Wright, Caradee Y. and Scovronick, Noah and Garland, Rebecca M. and Milojevic, Ai and Kyselý, Jan and Urban, Aleš and Orru, Hans and Indermitte, Ene and Jaakkola, Jouni J. K. and Ryti, Niilo R. I. and Katsouyanni, Klea and Analitis, Antonis and Zanobetti, Antonella and Schwartz, Joel and Chen, Jianmin and Wu, Tangchun and Cohen, Aaron and Gasparrini, Antonio and Kan, Haidong. (2019) Ambient particulate air pollution and daily mortality in 652 cities. The New England journal of medicine, 381 (8). pp. 705-715.

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Official URL: https://edoc.unibas.ch/71960/

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The systematic evaluation of the results of time-series studies of air pollution is challenged by differences in model specification and publication bias.; We evaluated the associations of inhalable particulate matter (PM) with an aerodynamic diameter of 10 μm or less (PM; 10; ) and fine PM with an aerodynamic diameter of 2.5 μm or less (PM; 2.5; ) with daily all-cause, cardiovascular, and respiratory mortality across multiple countries or regions. Daily data on mortality and air pollution were collected from 652 cities in 24 countries or regions. We used overdispersed generalized additive models with random-effects meta-analysis to investigate the associations. Two-pollutant models were fitted to test the robustness of the associations. Concentration-response curves from each city were pooled to allow global estimates to be derived.; On average, an increase of 10 μg per cubic meter in the 2-day moving average of PM; 10; concentration, which represents the average over the current and previous day, was associated with increases of 0.44% (95% confidence interval [CI], 0.39 to 0.50) in daily all-cause mortality, 0.36% (95% CI, 0.30 to 0.43) in daily cardiovascular mortality, and 0.47% (95% CI, 0.35 to 0.58) in daily respiratory mortality. The corresponding increases in daily mortality for the same change in PM; 2.5; concentration were 0.68% (95% CI, 0.59 to 0.77), 0.55% (95% CI, 0.45 to 0.66), and 0.74% (95% CI, 0.53 to 0.95). These associations remained significant after adjustment for gaseous pollutants. Associations were stronger in locations with lower annual mean PM concentrations and higher annual mean temperatures. The pooled concentration-response curves showed a consistent increase in daily mortality with increasing PM concentration, with steeper slopes at lower PM concentrations.; Our data show independent associations between short-term exposure to PM; 10; and PM; 2.5; and daily all-cause, cardiovascular, and respiratory mortality in more than 600 cities across the globe. These data reinforce the evidence of a link between mortality and PM concentration established in regional and local studies. (Funded by the National Natural Science Foundation of China and others.).
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health > Physical Hazards and Health (Röösli)
UniBasel Contributors:Ragettli, Martina
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Massachusetts Medical Society
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:18 Sep 2019 07:13
Deposited On:18 Sep 2019 07:13

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