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Synthesis of chiral nine and twelve-membered cyclic polyamines from natural building blocks

Müntener, Thomas and Thommen, Fabienne and Joss, Daniel and Kottelat, Jérémy and Prescimone, Alessandro and Häussinger, Daniel. (2019) Synthesis of chiral nine and twelve-membered cyclic polyamines from natural building blocks. Chemical Communications , 55 (32). pp. 4715-4718.

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Abstract

A rational strategy for the facile and efficient cyclization of amino acid-based linear precursors forming nine and twelve-membered cyclic peptidomimetics is reported. The resulting chiral lactams can readily be reduced to substituted cyclic polyamine analogues of 1,4,7,10-tetraaza-cyclododecane (cyclen) and 1,4,7-triaza-cyclononane (TACN).
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Nuclear Magnetic Resonance (Häussinger)
UniBasel Contributors:Häussinger, Daniel and Joss, Daniel and Müntener, Thomas and Prescimone, Alessandro
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Royal Society of Chemistry
ISSN:1359-7345
e-ISSN:1364-548X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
edoc DOI:
Last Modified:18 Jun 2019 14:08
Deposited On:18 Jun 2019 14:08

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