Baldus, Stephan E. and Zirbes, Thomas K. and Thiele, Juergen and Eming, Sabine A. and Henz, Beate M. and Hartmann, Karin. (2004) Altered apoptosis and cell cycling of mast cells in bone marrow lesions of patients with systemic mastocytosis. Haematologica, 89 (12). pp. 1525-1527.
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Official URL: https://edoc.unibas.ch/70836/
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Abstract
Enhanced expression of the apoptosis-preventing protein bcl-xL and the cell cycle-regulating protein p21 was observed in bone marrow infiltrates of systemic mastocytosis. Expression of bcl-2, Ki67, and p53 as well as ISEL apoptosis staining were comparable in patients with mastocytosis and in controls. An altered rate of apoptosis and cell cycling may contribute to accumulation of mast cells in mastocytosis.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Allergy and Immunity (Hartmann) |
|---|---|
| UniBasel Contributors: | Hartmann, Karin |
| Item Type: | Article, refereed |
| Article Subtype: | Further Journal Contribution |
| Publisher: | Ferrata Storti Foundation |
| ISSN: | 0390-6078 |
| e-ISSN: | 1592-8721 |
| Note: | Publication type according to Uni Basel Research Database: Journal item |
| Identification Number: |
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| Last Modified: | 10 Nov 2020 15:18 |
| Deposited On: | 10 Nov 2020 15:18 |
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