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Prevalence of Giardia intestinalis infection in schistosomiasis-endemic areas in South-Central Mali

Fofana, Hassan K. M. and Schwarzkopf, Maren and Doumbia, Mama N. and Saye, Rénion and Nimmesgern, Anna and Landouré, Aly and Traoré, Mamadou S. and Mertens, Pascal and Utzinger, Jürg and Sacko, Moussa and Becker, Sören L.. (2019) Prevalence of Giardia intestinalis infection in schistosomiasis-endemic areas in South-Central Mali. Tropical medicine and infectious disease, 4 (2). p. 86.

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Abstract

Intestinal parasite infections are frequent causes of diarrhea and malnutrition among children in the tropics. Transmission of helminths and intestinal protozoa is intimately connected with conditions of poverty, including inadequate sanitation and hygiene. Concurrent infections with several intestinal pathogens may lead to excess morbidity. Yet, there is a paucity of epidemiological data from Mali. In this study, stool samples from 56 individuals, aged 2-63 years, from Bamako and Niono, south-central Mali were examined for intestinal parasites using stool microscopy. Additionally, stool samples were subjected to a rapid diagnostic test (RDT) and polymerase chain reaction (PCR) for the detection of; Cryptosporidium; spp. and; Giardia intestinalis; . The predominant pathogens were; Schistosoma mansoni; and; G. intestinalis; with prevalences of 41% and 38%, respectively.; Hymenolepis nana; was detected in 4% of the participants, while no eggs of soil-transmitted helminths were found. Concurrent infections with; G. intestinalis; and; S. mansoni; were diagnosed in 16% of the participants. For the detection of; G. intestinalis; , PCR was more sensitive (100%) than RDT (62%) and microscopy (48%). As helminth-protozoa coinfections might have important implications for morbidity control programs, future studies should employ diagnostic tools beyond stool microscopy to accurately assess the co-endemicity of giardiasis and schistosomiasis.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Eco System Health Sciences > Health Impact Assessment (Utzinger)
UniBasel Contributors:Utzinger, Jürg and Becker, Sören Leif
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:MDPI
ISSN:2414-6366
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:28 Jun 2019 16:26
Deposited On:28 Jun 2019 16:26

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