Rapid spread of double East- and West-African kdr mutations in wild Anopheles coluzzi from Côte d'Ivoire

Mouhamadou, Chouaïbou Seïdou and N'Dri, Prisca Bédjou and Fodjo, Behi Kouadio and Sadia, Christabelle Gba and Affoue, France-Paraudie Kouadio and Koudou, Benjamin Guibehi. (2019) Rapid spread of double East- and West-African kdr mutations in wild Anopheles coluzzi from Côte d'Ivoire. Wellcome Open Research, 4. p. 31.

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Malaria morbidity and mortality rates in Sub-Saharan Africa are increasing. The scale-up of long-lasting insecticidal nets and indoor residual spraying have been the major contributors to the decrease of malaria burden. These tools are now threatened by insecticide resistance in malaria vectors, which is spreading dramatically. After two different real-time polymerase chain reaction molecular characterizations carried out on 70 mosquitoes sampled in the locality of Elibou in southern Côte d'Ivoire, results revealed that 9 mosquitoes from; Anopheles coluzzi; harbored the double East- and West-African knockdown resistance mutations. In the previous year, only 1 mosquito out of 150 sampled from 10 regions of the country had the same genotype. These results show the rapid spread of insecticide resistance in malaria vectors and highlight the urgent need to diversify the methods of vector control in order to avoid the failure of insecticide-based vector control tools which may favor malaria fatalities.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:N'Dri, Bedjou Prisca
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:28 May 2019 12:07
Deposited On:28 May 2019 12:07

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