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Stop making nonSense: the C. elegans smg genes

Mango, Susan E.. (2001) Stop making nonSense: the C. elegans smg genes. Trends in genetics : TIG, 17 (11). pp. 646-653.

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Official URL: https://edoc.unibas.ch/70590/

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Abstract

Cells monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated. In the nematode Caenorhabditis elegans, degradation by the mRNA surveillance pathway depends on seven smg genes. Three of these genes also have a role in a second mRNA degradation pathway called RNA interference (RNAi), which is triggered by double-stranded RNA (dsRNA). Here I describe what is known about the smg genes and their potential functions in these two mRNA degradation pathways.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell and Developmental Biology (Mango)
UniBasel Contributors:Mango, Susan Elizabeth
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:0168-9525
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:13 Nov 2020 08:56
Deposited On:13 Nov 2020 08:56

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