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Insufficient sensitivity of laser desorption-time of flight mass spectrometry-based detection of hemozoin for malaria screening

Christner, Martin and Frickmann, Hagen and Klupp, Eva and Rohde, Holger and Kono, Maya and Tannich, Egbert and Poppert, Sven. (2019) Insufficient sensitivity of laser desorption-time of flight mass spectrometry-based detection of hemozoin for malaria screening. Journal of Microbiological Methods, 160. pp. 104-106.

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Official URL: https://edoc.unibas.ch/70287/

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Abstract

Laser desorption-time of flight (LD-TOF) mass spectrometry-based detection of hemozoin was assessed for its performance characteristics as a rapid screening test for malaria. In spite of good specificity of >95%, poor sensitivity of 80.2% for microscopically positive samples makes the easy-to-apply and rapid approach unsuitable for the routine diagnostic setting.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Medicine > Diagnostic (Marti)
UniBasel Contributors:Poppert, Sven
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:0167-7012
e-ISSN:1872-8359
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:25 Apr 2019 08:18
Deposited On:25 Apr 2019 08:18

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