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Enzymatic Reactions in Polymeric Nanocontainers: Nanotechnology meets Nature

Beluatti, Andrea and Carciun, Ioana and Meyer, Claire E. and Rigo, Serena and Palivan, Cornelia G.. (2019) Enzymatic Reactions in Polymeric Nanocontainers: Nanotechnology meets Nature. Current Opinion in Biotechnology, 60. pp. 53-62.

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Official URL: https://edoc.unibas.ch/70071/

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Abstract

One of the main features of living matter is compartmentalization, that is the temporal and spatial division of biological reactions and containment of the cellular components. Nanotechnology aims to replicate this, separating tiny environments from the exterior into nano-sized and micro-sized self-assembled compartments. Those synthetic compartments can perform reactions, be tracked and act in vivo. Here, an overview of the techniques to fabricate vesicular, polymer-based catalytic compartments and the parameters affecting their architecture is presented. How communication can be ensured across their membranes, recent developments in the enzymes that have been loaded into them and the latest advances in biological applications are discussed. This review highlights the characteristics that make polymers an enticing choice, the protection they offer, and their applications in compartmentalizing biologically relevant reactions.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
05 Faculty of Science > Departement Chemie > Chemie > Physikalische Chemie (Palivan)
UniBasel Contributors:Palivan, Cornelia G
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:0958-1669
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:22 Aug 2019 14:20
Deposited On:22 Aug 2019 14:20

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