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Generation of treatment plans for Magnetic Resonance guided High Intensity Focused Ultrasound (MRgHIFU) in the liver

Möri, Nadia. Generation of treatment plans for Magnetic Resonance guided High Intensity Focused Ultrasound (MRgHIFU) in the liver. 2018, Doctoral Thesis, University of Basel, Faculty of Medicine.

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Official URL: http://edoc.unibas.ch/diss/DissB_13002

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Abstract

In this thesis, the self-scanning method is proposed to handle organ motion. It takes advantage of the perpetual respiratory motion to passively scan the tumor. In other
words, we are placing the static focal point of the HIFU into the tumor. The motion caused by breathing shifts the tumor through this focal point. We anticipate at which time point tumor tissue is located under the focal spot and modulate the HIFU intensity based on this information. Once the tumor has been ablated along the self-scanned trajectory, the focal spot is relocated to a different but static position within the body. With this method, we combine the advantages of the gating and the tracking method: a HIFU device with a fixed focus can be used and a high duty cycle is achieved. Moreover, since with the self-scanning approach no lateral steering of the focal spot is required, fewer secondary lobes are generated and position-dependent decay of the focal spot intensity during lateral steering is avoided. However, this comes at the cost of an increased complexity at the planning stage.
Advisors:Cattin, Philippe and Bieri, Oliver and Jud, Christoph
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Imaging and Computational Modelling > Center for medical Image Analysis & Navigation (Cattin)
UniBasel Contributors:Bieri, Oliver and Jud, Christoph
Item Type:Thesis
Thesis Subtype:Doctoral Thesis
Thesis no:13002
Thesis status:Complete
Bibsysno:Link to catalogue
Number of Pages:1 Online-Ressource (ix, 102 Seiten)
Language:English
Identification Number:
Last Modified:17 Apr 2019 04:30
Deposited On:16 Apr 2019 12:46

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