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Dynamics and force generation of flagellum and pili in Caulobacter crescentus

Sauter, Nora. Dynamics and force generation of flagellum and pili in Caulobacter crescentus. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

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Official URL: http://edoc.unibas.ch/diss/DissB_13009

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Abstract

Surface attachment of bacteria is the first step of biofilm formation and biofilms are associated with infections and bacterial resistance. Surface attachment of bacteria is often mediated by extracellular appendages, for example flagellum and pili. The flagellum is a cork-screw like structure used for swimming and surface sensing. Pili are filamentous structures and have a wide variety of functions, among them attachment on surfaces. Because of the small diameter of flagellum and pili, direct observations of flagellum and pili are challenging under physiological conditions.
C. crescentus, a model organism for biofilm formation, has an asymmetric life cycle. The sessile and stalked mother cell produces a motile daughter cell that is equipped with a flagellum and pili at the free pole.
In this work we investigated the dynamics and force generation of the flagellum and pili of C. crescentus under physiological conditions employing a label-free method.
Advisors:Jenal, Urs and Pfohl, Thomas and Braun, Thomas
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Molecular Microbiology (Jenal)
05 Faculty of Science > Departement Biozentrum > Growth & Development > Molecular Microbiology (Jenal)
UniBasel Contributors:Jenal, Urs and Pfohl, Thomas and Braun, Thomas
Item Type:Thesis
Thesis Subtype:Doctoral Thesis
Thesis no:13009
Thesis status:Complete
Bibsysno:Link to catalogue
Number of Pages:1 Online-Ressource (161 Seiten)
Language:English
Identification Number:
Last Modified:07 May 2019 04:30
Deposited On:06 May 2019 14:10

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