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Grey matters: Mapping the transition to psychosis

Borgwardt, Stefan and Fusar Poli, Paolo and Riecher-Rössler, Anita and McGuire, Philip. (2012) Grey matters: Mapping the transition to psychosis. In: Vulnerability to Psychosis - From Neurosciences to Psychopathology. Hove, pp. 95-104.

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Official URL: https://edoc.unibas.ch/68320/

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Abstract

Despite many neuroimaging studies on schizophrenia showing brain abnormalities the exact time course of their occurrence is unknown. Studies of gray matter are a powerful tool in biological psychiatry and provide an unprecedented opportunity for brain structure investigations. Here we compared cross-sectional and longitudinal structural neuroimaging studies distinguishing high-risk subjects developing psychosis from those who did not. These investigations on gray matter volumes in the prodromal phase potentially identify core structural markers of impending psychoses and clarify dynamic changes underlying the transition. Subjects at high risk of psychosis show qualitatively similar albeit less severe gray matter abnormalities as patients with psychosis.
Faculties and Departments:03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Riecher-Rössler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Riecher-Rössler)
UniBasel Contributors:Riecher-Rössler, Anita
Item Type:Book Section
Book Section Subtype:Further Contribution in a Book
Publisher:Psychology Press
ISBN:978-1-8487-2087-9
e-ISBN:978-1-8487-2087-4
Series Name:Maudsley Series
Note:Publication type according to Uni Basel Research Database: Book item
Language:English
Last Modified:04 Jun 2019 15:04
Deposited On:07 Mar 2019 10:37

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