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The role of behavioral inhibition, perceived parental rearing, and adverse life events in adolescents and young adults with incident obsessive-compulsive disorder

Hofer, Patrizia D. and Wahl, Karina and Meyer, Andrea H. and Miché, Marcel and Beesdo-Baum, Katja and Wittchen, Hans-Ulrich and Lieb, Roselind. (2018) The role of behavioral inhibition, perceived parental rearing, and adverse life events in adolescents and young adults with incident obsessive-compulsive disorder. Journal of obsessive-compulsive and related disorders, 19. pp. 116-123.

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Official URL: https://edoc.unibas.ch/67527/

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Abstract

The role of behavioral inhibition (BI), parental rearing, and adverse life events in the development of ob- sessive-compulsive disorder (OCD) is unresolved. We prospectively examined whether BI and perceived parental rearing predicted the subsequent first onset of OCD and whether BI moderated the association between per- ceived parental rearing/adverse life events and the first onset of OCD. Data come from a prospective-longitudinal study among community adolescents and young adults (aged 14-24) who were followed up over 10 years (N = 2210). OCD and adverse life events were assessed with the DSM-IV/M-CIDI. BI and parental rearing were assessed by self-report. In adjusted logistic regressions, BI (risk ratio, RR = 8.8,95% confidence interval, CI, [3.3,23.2]), both the social (RR=2.6,95%CI[1.04,6.3]) and nonsocial fear (RR=4.5,95%CI[2.3,8.6]) com- ponents, and paternal rejection (RR = 3.9,95%CI[1.6,9.7]) predicted OCD. Social BI moderated the association of adverse life event (RR = 11.98,95%CI[1.8,82.1]) and paternal overprotection (RR = 5.5,95%CI[2.1,14.8]) with OCD. Nonsocial fear BI moderated the association between paternal emotional warmth (RR = 0.37,95%CI [0.1,0.99]) and OCD. BI and paternal rejection were associated with an increased risk of first onset of OCD. Individuals with high social BI who experienced paternal overprotection or any adverse life events may profit from early targeted prevention. Emotional warmth may buffer the association between nonsocial fear BI and OCD.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Klinische Psychologie und Epidemiologie (Lieb)
UniBasel Contributors:Miché, Marcel and Wahl, Karina and Hofer, Patrizia D
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:2211-3649
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:28 Sep 2020 11:01
Deposited On:10 Jan 2019 16:11

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