Analyzing the interaction of pathogens with the host immune system

Jayachandran, R. and Scherr, N. and Pieters, J.. (2009) Analyzing the interaction of pathogens with the host immune system. Immunology letters, Vol. 122 (2). pp. 112-114.

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Infectious diseases continue to represent a great burden to human society, being responsible for approximately 14 to 16 million deaths annually. Today, Mycobacterium tuberculosis, the causative agent of tuberculosis, remains one of the most important infectious agents. Moreover, with the emergence of multi drug and extensive drug resistant strains of M. tuberculosis, there is a great need for a better understanding of the virulence strategies utilized by this pathogen. In this manuscript, we discuss some of the strategies that have been followed to unravel virulence mechanisms utilized by M. tuberculosis. Knowledge of these mechanisms is important to reveal potential targets that may be useful for the development of compounds to treat tuberculosis.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Biochemistry (Pieters)
UniBasel Contributors:Pieters, Jean
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:14 Nov 2017 14:03
Deposited On:22 Mar 2012 13:35

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