Associations of Hospital Length of Stay with Surgical Site Infections

Mujagic, Edin and Marti, Walter R. and Coslovsky, Michael and Soysal, Savas D. and Mechera, Robert and von Strauss, Marco and Zeindler, Jasmin and Saxer, Franziska and Mueller, Alexandra and Fux, Christoph A. and Kindler, Christoph and Gurke, Lorenz and Weber, Walter P.. (2018) Associations of Hospital Length of Stay with Surgical Site Infections. World Journal of Surgery. p. 9.

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Surgical site infections (SSI) are a major cause of morbidity and mortality in surgical patients. Postoperative and total hospital length of stay (LOS) are known to be prolonged by the occurrence of SSI. Preoperative LOS may increase the risk of SSI. This study aims at identifying the associations of pre- and postoperative LOS in hospital and intensive care with the occurrence of SSI.; This observational cohort study includes general, orthopedic trauma and vascular surgery patients at two tertiary referral centers in Switzerland between February 2013 and August 2015. The outcome of interest was the 30-day SSI rate.; We included 4596 patients, 234 of whom (5.1%) experienced SSI. Being admitted at least 1 day before surgery compared to same-day surgery was associated with a significant increase in the odds of SSI in univariate analysis (OR 1.65, 95% CI 1.25-2.21, p < 0.001). More than 1 day compared to 1 day of preoperative hospital stay did not further increase the odds of SSI (OR 1.08, 95% CI 0.77-1.50, p = 0.658). Preoperative admission to an intensive care unit (ICU) increased the odds of SSI as compared to hospital admission outside of an ICU (OR 2.19, 95% CI 0.89-4.59, p = 0.057). Adjusting for potential confounders in multivariable analysis weakened the effects of both preoperative admission to hospital (OR 1.38, 95% CI 0.99-1.93, p = 0.061) and to the ICU (OR 1.89, 95% CI 0.73-4.24, p = 0.149).; There was no significant independent association between preoperative length of stay and risk of SSI while SSI and postoperative LOS were significantly associated.
Faculties and Departments:03 Faculty of Medicine
03 Faculty of Medicine > Bereich Operative Fächer (Klinik)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Operative Fächer (Klinik)
UniBasel Contributors:Zeindler, Jasmin
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:05 Oct 2018 14:09
Deposited On:05 Oct 2018 14:09

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