Bless, Philipp Justus. Epidemiology of campylobacteriosis and acute gastroenteritis from a human and health system's perspective in Switzerland. 2017, Doctoral Thesis, University of Basel, Faculty of Science.
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Official URL: http://edoc.unibas.ch/diss/DissB_12702
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Abstract
In humans, the zoonotic disease campylobacteriosis is caused by an infection with Campylobacter spp. The infection often leads to acute gastroenteritis (AG), a syndrome which is characterised by diarrhoea, nausea and other gastrointestinal symptoms. Infectious intestinal diseases (IID) other than campylobacteriosis such as salmonellosis or norovirus infections can also result in AG. The disease and health system burden of campylobacteriosis and AG in general is considerable and around 230,000 cases of campylobacteriosis alone are recorded annually in Europe.
In Switzerland, the surveillance of IID is based on a mandatory notification system for laboratory-confirmed cases of certain IIDs while there is no distinct surveillance of AG. About 7000 cases of campylobacteriosis and 1200 cases of salmonellosis are recorded annually in the Swiss notification system. Cases suffering from a mild episode of IID often do not seek health care and consequently are never diagnosed and recorded. As a result the entire disease and health system burden of AG caused by IID is unknown. The present PhD thesis assesses causes for an infection with Campylobacter spp. in wintertime and the disease and health system burden of IID and AG at the primary care level in Switzerland. Determinants for the registration of IID cases along the burden-of-illness pyramid and the case management of AG patients in primary care are also explored.
In Switzerland, the surveillance of IID is based on a mandatory notification system for laboratory-confirmed cases of certain IIDs while there is no distinct surveillance of AG. About 7000 cases of campylobacteriosis and 1200 cases of salmonellosis are recorded annually in the Swiss notification system. Cases suffering from a mild episode of IID often do not seek health care and consequently are never diagnosed and recorded. As a result the entire disease and health system burden of AG caused by IID is unknown. The present PhD thesis assesses causes for an infection with Campylobacter spp. in wintertime and the disease and health system burden of IID and AG at the primary care level in Switzerland. Determinants for the registration of IID cases along the burden-of-illness pyramid and the case management of AG patients in primary care are also explored.
Advisors: | Tanner, Marcel and Mäusezahl, Daniel and Chappuis, François |
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Faculties and Departments: | 05 Faculty of Science 03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Malaria Vaccines (Tanner) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Malaria Vaccines (Tanner) |
UniBasel Contributors: | Tanner, Marcel and Mäusezahl, Daniel |
Item Type: | Thesis |
Thesis Subtype: | Doctoral Thesis |
Thesis no: | 12702 |
Thesis status: | Complete |
Number of Pages: | 1 Online-Ressource (xxxii, 359 Seiten) |
Language: | English |
Identification Number: |
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edoc DOI: | |
Last Modified: | 17 Aug 2018 04:30 |
Deposited On: | 16 Aug 2018 08:27 |
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