A model of host response to a multi-stage pathogen
Date Issued
2011-01-01
Author(s)
Shapiro, Michael
DOI
10.1007/s00285-010-0365-5
Abstract
We model the immune surveillance of a pathogen which passes through n immunologically distinct stages. The biological parameters of this system induce a partial order on the stages, and this, in turn, determines which stages will be subject to immune regulation. This corresponds to the system's unique asymptotically stable fixed point.