Molecular targets to treat muscular dystrophies

Kinter, Jochen and Sinnreich, Michael. (2014) Molecular targets to treat muscular dystrophies. Swiss medical weekly, 144. w13916.

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Muscular dystrophies are classically subdivided according to their clinical phenotype, and were historically defined as progressive myopathies in which muscle biopsies demonstrate muscle fibre necrosis and regeneration, as well as replacement of muscle fibres by adipose and connective tissue. In recent years, great progress has been made in identifying the genetic basis of many myopathies, thereby presenting opportunities to develop therapeutic strategies that act on specific molecular pathomechanisms. The different therapeutic strategies and their molecular targets will be reviewed.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Neuromuscular Research (Sinnreich)
UniBasel Contributors:Sinnreich, Michael
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Publisher:EMH Swiss Medical Publishers
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:04 Aug 2020 12:12
Deposited On:04 Aug 2020 12:12

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