Radulovic, K. and Niess, J. H.. (2015) CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment? Journal of Immunology Research, 2015. p. 497056.
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Official URL: https://edoc.unibas.ch/62391/
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Abstract
CD69 has been identified as an early activation marker of lymphocytes. However, recent work has indicated that CD69 plays an essential role for the regulation of inflammatory processes. Particularly, CD69 is highly expressed by lymphocytes at mucosal sites being constantly exposed to the intestinal microflora (one of the nature's most complex and most densely populated microbial habitats) and food antigens, while only a small number of circulating leukocytes express this molecule. In this review we will discuss the role of CD69 in mucosal tissue and consider CD69 as a potential target for the development of novel treatments of intestinal inflammation.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Gastroenterology DBM (Niess) |
|---|---|
| UniBasel Contributors: | Niess, Jan Hendrik |
| Item Type: | Article, refereed |
| Article Subtype: | Further Journal Contribution |
| ISSN: | 2314-8861 |
| e-ISSN: | 2314-7156 |
| Note: | Publication type according to Uni Basel Research Database: Journal item |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 11 Dec 2018 16:39 |
| Deposited On: | 11 Dec 2018 16:39 |
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