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Laser scoop desobliteration: a method for minimally invasive remote recanalization of chronically occluded superficial femoral arteries

Heneweer, Carola and Siggelkow, Markus and Helle, Michael and Petzina, Rainer and Wulff, Asmus and Schaefer, Joost P. and Berndt, Rouven and Rusch, Rene and Wedel, Thilo and Klaws, Guenther and Muller-Gerbl, Magdalena and Rocken, Christoph and Jansen, Olav and Lutter, Georg and Cremer, Joachim and Gross, Justus. (2015) Laser scoop desobliteration: a method for minimally invasive remote recanalization of chronically occluded superficial femoral arteries. Journal of Biomedical Optics, 20 (2). p. 25005.

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Official URL: https://edoc.unibas.ch/62376/

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Abstract

Stenosis and occlusion of the superficial femoral artery (SFA) are most common in arterial occlusive disease. There are numerous interventional, surgical, and combined approaches to reconstitute maximum blood supply to the lower limb; however, despite intense clinical research, the long-term success rates are still poor. We present the first results with a catheter prototype for laser-based minimal invasive endarterectomy, called laser scoop desobliteration (LSD). The tip of a glass fiber containing a catheter was modified with a spatula head design and connected to an ultraviolet laser. It was tested in cadavers fixed with the Thiel embalming technique preserving tissue consistency, flexibility, and plasticity. After longitudinal arteriotomy of the SFA, a circular dissection between media and adventitia was performed. Then the LSD catheter was inserted and propagated with a progress of 1 mms. Afterward, the atheroma core, which showed a plain surface without substantial attaching tissue debris, was removed. Histological examination of the vessel wall showed that the dissection was performed at the media/adventitia interface. In summary, the constructed LSD catheter allowed a rapid and easy way to perform an endarterectomy, thereby offering an innovative approach in the treatment of chronic occluded SFA.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Division of Anatomy > Musculosceletal Research (Müller-Gerbl)
UniBasel Contributors:Müller-Gerbl, Magdalena
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:1560-2281 (Electronic) 1083-3668 (Linking)
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Dec 2018 10:10
Deposited On:01 Dec 2018 10:10

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