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MAGE-A Antigens and Cancer Immunotherapy

Zajac, Paul and Schultz-Thater, Elke and Tornillo, Luigi and Sadowski, Charlotte and Trella, Emanuele and Mengus, Chantal and Iezzi, Giandomenica and Spagnoli, Giulio C.. (2017) MAGE-A Antigens and Cancer Immunotherapy. Frontiers in Medicine (Lausanne), 4. p. 18.

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Official URL: https://edoc.unibas.ch/61930/

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Abstract

MAGE-A antigens are expressed in a variety of cancers of diverse histological origin and germinal cells. Due to their relatively high tumor specificity, they represent attractive targets for active specific and adoptive cancer immunotherapies. Here, we (i) review past and ongoing clinical studies targeting these antigens, (ii) analyze advantages and disadvantages of different therapeutic approaches, and (iii) discuss possible improvements in MAGE-A-specific immunotherapies.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Cancer Immunotherapy (Iezzi)
UniBasel Contributors:Iezzi, Giandomenica
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:2296-858X (Print) 2296-858X (Linking)
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:29 Jun 2019 11:09
Deposited On:29 Jun 2019 11:09

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