edoc

Prenatal and postnatal medical conditions and the risk of brain tumors in children and adolescents : an international multicenter case-control study

Tettamanti, Giorgio and Shu, Xiaochen and Adel Fahmideh, Maral and Schüz, Joachim and Röösli, Martin and Tynes, Tore and Grotzer, Michael and Johansen, Christoffer and Klaeboe, Lars and Kuehni, Claudia E. and Lannering, Birgitta and Schmidt, Lisbeth S. and Vienneau, Danielle and Feychting, Maria. (2017) Prenatal and postnatal medical conditions and the risk of brain tumors in children and adolescents : an international multicenter case-control study. Cancer epidemiology biomarkers & prevention, 26 (1). pp. 110-115.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/61121/

Downloads: Statistics Overview

Abstract

Previous studies have evaluated the effect of medical diagnostic radiation on brain tumors. Recent cohort studies have reported an increased risk associated with exposure to head CT scans.; Information regarding medical conditions, including prenatal and postnatal exposure to medical diagnostic radiation, was obtained from CEFALO, a multicenter case-control study performed in Denmark, Norway, Sweden, and Switzerland through face-to-face interview. Eligible cases of childhood and adolescent brain tumors (CABT) were ages 7 to 19 years, diagnosed between January 1, 2004 and August 31, 2008, and living in the participating countries (n = 352). The cases were matched by age, sex, and region to 646 population-based controls.; Prenatal exposure to medical diagnostic radiation and postnatal exposure to X-rays were not associated with CABTs. A higher risk estimate of CABTs, although not statistically significant, was found for exposure to head CT scan (OR, 1.86; 95% confidence interval, 0.82-4.22). The associations with head injury, febrile seizure, fever in the first 12 weeks, and general anesthesia were close to unity.; Prenatal or postnatal medical conditions, including medical diagnostic radiation, were not associated with CABTs. On the basis of small numbers of exposed children, we observed a nonsignificant increased risk for CT scans of the head.; We have presented additional evidence, suggesting that exposure to head CT scan may be associated with the occurrence of CABTs. Cancer Epidemiol Biomarkers Prev; 26(1); 110-5. ©2016 AACR.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health Systems Research > Physical Hazards and Health (Röösli)
UniBasel Contributors:Vienneau, Danielle and Röösli, Martin
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:American Association for Cancer Research
ISSN:1055-9965
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:23 Feb 2018 14:53
Deposited On:24 Apr 2017 13:45

Repository Staff Only: item control page