Physiological parameters after nonpharmacological analgesia in preterm infants: a randomized trial

Gerull, Roland and Cignacco, Eva and Stoffel, Liliane and Sellam, Gila and Nelle, Mathias. (2013) Physiological parameters after nonpharmacological analgesia in preterm infants: a randomized trial. Acta Paediatrica, 102 (8). e368-e373.

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Official URL: https://edoc.unibas.ch/60849/

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To compare the influence of three different nonpharmacological interventions on cortical activation, heart rate and peripheral oxygen saturation (SaO2 ) after heelstick in preterm infants.; Twenty five preterm infants between 24 0/7 and 32 0/7 weeks of gestational age were randomized to either oral sucrose (S), facilitated tucking (FT) or a combination of the two interventions (SFT) prior to five heelsticks each within the first 14 days of life. SaO2 , heart rate and oxygenation of the somatosensory cortex, measured by near infrared spectroscopy (NIRS), were analysed.; Hundred and twenty five heelsticks were performed. The heart rate increased significantly after heelstick in all three intervention groups (p < 0.004 in all groups). The increase was higher in the FT group compared with the other groups (S: p = 0.007; SFT: p = 0.004). There was no difference among the two groups receiving sucrose (S and SFT; p = 0.87). SaO2 did not change significantly after heelstick in all intervention groups. Near infrared spectroscopy measurements did not show a significant change in the curve but patients in the FT group showed a trend towards higher average oxygenation of the contralateral somatosensory cortex.; Oral sucrose seems to be more effective in reducing reaction to pain than FT. Application of both interventions did not show an additive effect.
Faculties and Departments:03 Faculty of Medicine > Departement Public Health > Institut für Pflegewissenschaft
UniBasel Contributors:Cignacco, Eva
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:16 Jul 2020 13:20
Deposited On:16 Jul 2020 13:20

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