Threshold analysis in the presence of both the diagnostic and the therapeutic risk

Felder, Stefan and Mayrhofer, Thomas. (2018) Threshold analysis in the presence of both the diagnostic and the therapeutic risk. The European journal of health economics, 19 (7). pp. 1019-1026.

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Official URL: http://edoc.unibas.ch/58475/

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The well-established a priori probability of illness threshold in medical decision making, introduced by Pauker and Kassirer (N Engl J Med 293:229–234, 1975; N Engl J Med 302:1109–1117, 1980), involves the diagnostic risk only. We generalize the threshold analysis by adding the therapeutic risk, i.e., in accounting for the risk that a treatment might sometimes fail. We derive a priori probability of illness threshold as a function of the probability of successful treatment, as well as the inverted function, where the successful treatment probability threshold is a function of the a priori probability of illness. The thresholds in the general model are higher than those in the special cases where one of the two risks is absent. Applications show that the changes in the thresholds can be substantial. Our general model might explain empirical findings of much higher thresholds than the Pauker–Kassirer model suggests.
Faculties and Departments:06 Faculty of Business and Economics > Departement Wirtschaftswissenschaften > Professuren Wirtschaftswissenschaften > Health Economics (Felder)
UniBasel Contributors:Felder, Stefan
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:29 Jan 2019 08:12
Deposited On:14 Jun 2018 10:10

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