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Mental disorders and the risk for the subsequent first suicide attempt: results of a community study on adolescents and young adults

Miché, Marcel and Hofer, Patrizia Denise and Voss, Catharina and Meyer, Andrea Hans and Gloster, Andrew Thomas and Beesdo-Baum, Katja and Lieb, Roselind. (2018) Mental disorders and the risk for the subsequent first suicide attempt: results of a community study on adolescents and young adults. European Child and Adolescent Psychiatry, 27 (7). pp. 839-848.

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Abstract

Adolescents and young adults represent the high-risk group for first onset of both DSM-IV mental disorders and lifetime suicide attempt (SA). Yet few studies have evaluated the temporal association of prior mental disorders and subsequent first SA in a young community sample. We examined (a) such associations using a broad range of specific DSM-IV mental disorders, (b) the risk of experiencing the outcome due to prior comorbidity, and (c) the proportion of SAs that could be attributed to prior disorders. During a 10-year prospective study, data were gathered from 3021 community subjects, 14-24 years of age at baseline. DSM-IV disorders and SA were assessed with the Munich-Composite International Diagnostic Interview. Cox models with time-dependent covariates were used to estimate the temporal associations of prior mental disorders with subsequent first SA. Most prior mental disorders showed elevated risk for subsequent first SA. Highest risks were associated with posttraumatic stress disorder (PTSD), dysthymia, and nicotine dependence. Comorbidity elevated the risk for subsequent first SA, and the more disorders a subject had, the higher the risk for first SA. More than 90% of SAs in the exposed group could be attributed to PTSD, and over 30% of SAs in the total sample could be attributed to specific phobia. Several DSM-IV disorders increase the risk for first SA in adolescents and young adults. Several promising early intervention targets were observed, e.g., specific phobia, nicotine dependence, dysthymia, and whether a young person is burdened with comorbid mental disorders.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Clinical Psychology and Intervention Science (Gloster)
07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Klinische Psychologie und Epidemiologie (Lieb)
07 Faculty of Psychology
UniBasel Contributors:Miché, Marcel and Lieb, Roselind and Hofer, Patrizia D and Meyer, Andrea Hans and Gloster, Andrew
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Springer
ISSN:1018-8827
e-ISSN:1435-165X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
edoc DOI:
Last Modified:17 Sep 2020 03:10
Deposited On:29 May 2018 13:59

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