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MRCZ - A file format for cryo-TEM data with fast compression

McLeod, Robert A. and Diogo Righetto, Ricardo and Stewart, Andy and Stahlberg, Henning. (2018) MRCZ - A file format for cryo-TEM data with fast compression. Journal of Structural Biology, 201 (3). pp. 252-257.

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Abstract

The introduction of fast CMOS detectors is moving the field of transmission electron microscopy into the computer science field of big data. Automated data pipelines control the instrument and initial processing steps which imposes more onerous data transfer and archiving requirements. Here we conduct a technical demonstration whereby storage and read/write times are improved 10× at a dose rate of 1 e-/pix/frame for data from a Gatan K2 direct-detection device by combination of integer decimation and lossless compression. The example project is hosted at github.com/em-MRCZ and released under the BSD license.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Structural Biology & Biophysics > Structural Biology (Stahlberg)
UniBasel Contributors:Stahlberg, Henning
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:1047-8477
e-ISSN:1095-8657
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:10 Jul 2018 12:33
Deposited On:16 May 2018 08:35

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