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Mycobacterium tuberculosis and the macrophage : maintaining a balance

Pieters, J.. (2008) Mycobacterium tuberculosis and the macrophage : maintaining a balance. Cell Host & Microbe, 3 (6). pp. 399-407.

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Official URL: http://edoc.unibas.ch/dok/A5259389

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Abstract

Mycobacterium tuberculosis is a highly efficient pathogen, killing millions of infected people annually. The capacity of M. tuberculosis to survive and cause disease is strongly correlated to their ability to escape immune defense mechanisms. In particular, M. tuberculosis has the remarkable capacity to survive within the hostile environment of the macrophage. Understanding M. tuberculosis virulence strategies will not only define novel targets for drug development but will also help to uncover previously unknown signaling pathways related to the host's response to M. tuberculosis infection.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Biochemistry (Pieters)
UniBasel Contributors:Pieters, Jean
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Cell Press
ISSN:1931-3128
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Language:English
Identification Number:
edoc DOI:
Last Modified:18 Dec 2019 12:35
Deposited On:22 Mar 2012 13:31

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