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The exposome in practice : design of the EXPOsOMICS project

Vineis, P. and Chadeau-Hyam, M. and Gmuender, H. and Gulliver, J. and Herceg, Z. and Kleinjans, J. and Kogevinas, M. and Kyrtopoulos, S. and Nieuwenhuijsen, M. and Phillips, D. H. and Probst-Hensch, N. and Scalbert, A. and Vermeulen, R. and Wild, C. P. and ExposOmics Consortium, . (2017) The exposome in practice : design of the EXPOsOMICS project. International journal of hygiene and environmental health, 220 (2 Pt A). pp. 142-151.

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Official URL: http://edoc.unibas.ch/55145/

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Abstract

EXPOsOMICS is a European Union funded project that aims to develop a novel approach to the assessment of exposure to high priority environmental pollutants, by characterizing the external and the internal components of the exposome. It focuses on air and water contaminants during critical periods of life. To this end, the project centres on 1) exposure assessment at the personal and population levels within existing European short and long-term population studies, exploiting available tools and methods which have been developed for personal exposure monitoring (PEM); and 2) multiple "omic" technologies for the analysis of biological samples (internal markers of external exposures). The search for the relationships between external exposures and global profiles of molecular features in the same individuals constitutes a novel advancement towards the development of "next generation exposure assessment" for environmental chemicals and their mixtures. The linkage with disease risks opens the way to what are defined here as 'exposome-wide association studies' (EWAS).
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
UniBasel Contributors:Probst Hensch, Nicole
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:1438-4639
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:06 Jun 2017 12:22
Deposited On:06 Jun 2017 12:22

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