Validating the children's depression inventory in the context of Rwanda

Binagwaho, Agnes and Fawzi, Mary C. Smith and Agbonyitor, Mawuena and Nsanzimana, Sabin and Karema, Corine and Remera, Eric and Mutabazi, Vincent and Shyirambere, Cyprien and Cyamatare, Patrick and Nutt, Cameron and Wagner, Claire and Condo, Jeanine and Misago, Nancy and Kayiteshonga, Yvonne. (2016) Validating the children's depression inventory in the context of Rwanda. BMC pediatrics, 16. p. 29.

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Depression is often co-morbid with chronic conditions, and when combined with HIV it can increase progression and reduce survival. A brief and accurate screening tool for depression among children living with HIV is necessary to increase access to mental health care and improve HIV-related outcomes in the long-term.; A validation study was conducted, comparing the Children's Depression Inventory (CDI) with a structured clinical assessment as the gold standard among children living with HIV ages 7-14 years in Rwanda. The response rate was 87 % and the analysis was performed among 100 study participants.; Twenty-five percent of children had a diagnosis of depression based on the clinical interview. Sensitivity of the CDI ranged from 44 to 76 % and specificity was 92 to 100 % for cut-off scores from 5 to 9. The area under the curve (AUC) for receiver operating characteristic analysis, an estimate of overall accuracy, was 0.87 (95 % confidence interval: 0.77 - 0.97).; The significant prevalence of depression among children living with HIV in Rwanda reflects a critical need to advance mental health care in this population. Although overall accuracy of the CDI is reasonable in this context, further research needs to be done to develop a more sensitive measure of depression in this vulnerable population. Development of a highly sensitive screening measure will be a fundamental step towards improving access to mental health care among children living with HIV, potentially improving health outcomes and quality of life in the long-term as this vulnerable population transitions into adulthood.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:Karema, Corine Kakizi and Nsanzimana, Sabin
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:BioMed Central
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:16 Jul 2018 08:06
Deposited On:20 Apr 2017 13:37

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