edoc

T cell receptor-transgenic mouse models for studying cellular immune responses to Salmonella in vivo

Bumann, D.. (2003) T cell receptor-transgenic mouse models for studying cellular immune responses to Salmonella in vivo. FEMS Immunology and Medical Microbiology, 37 (2-3). pp. 105-109.

[img]
Preview
PDF - Published Version
164Kb

Official URL: http://edoc.unibas.ch/dok/A5259815

Downloads: Statistics Overview

Abstract

Cellular immune responses are crucial both for protective immunity against salmonellosis, and for the immunogenicity of oral vaccines based on avirulent live Salmonella as antigen carriers. The crucial early steps of T cell induction are difficult to investigate in conventional animals, but recently developed T cell receptor (TCR)-transgenic models allow visualization of antigen-specific T cells in vivo while they become induced. In this review, the results obtained with four different TCR-transgenic Salmonella infection models are described, and advantages and potential limits of each of the different models are compared.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Molecular Microbiology (Bumann)
UniBasel Contributors:Bumann, Dirk
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0928-8244
e-ISSN:1574-695X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:27 Nov 2017 08:07
Deposited On:22 Mar 2012 13:30

Repository Staff Only: item control page