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Reaction front propagation of actin polymerization in a comb-reaction system

Iomin, A. and Zaburdaev, V. and Pfohl, T.. (2016) Reaction front propagation of actin polymerization in a comb-reaction system. Chaos, Solitons & Fractals, 92. pp. 115-122.

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Official URL: http://edoc.unibas.ch/51783/

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Abstract

We develop a theoretical model of anomalous transport with polymerization-reaction dynamics. We are motivated by the experimental problem of actin polymerization occurring in a microfluidic device with a comb-like geometry. Depending on the concentration of reagents, two limiting regimes for the propagation of reaction are recovered: the failure of the reaction front propagation and a finite speed of the reaction front corresponding to the Fisher-Kolmogorov-Petrovskii-Piscounov (FKPP) at the long time asymptotic regime. To predict the relevance of these regimes we obtain an explicit expression for the transient time as a function of geometry and parameters of the experimental setup. Explicit analytical expressions of the reaction front velocity are obtained as functions of the experimental setup.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Biophysikalische Chemie (Pfohl)
UniBasel Contributors:Pfohl, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:0960-0779
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:09 Jan 2017 15:18
Deposited On:09 Jan 2017 15:18

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