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Motility, Force Generation, and Energy Consumption of Unicellular Parasites

Hochstetter, Axel and Pfohl, Thomas. (2016) Motility, Force Generation, and Energy Consumption of Unicellular Parasites. Trends in Parasitology, 32 (7). pp. 531-541.

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Official URL: http://edoc.unibas.ch/51781/

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Abstract

Motility is a key factor for pathogenicity of unicellular parasites, enabling them to infiltrate and evade host cells, and perform several of their life-cycle events. State-of-the-art methods of motility analysis rely on a combination of optical tweezers with high-resolution microscopy and microfluidics. With this technology, propulsion forces, energies, and power generation can be determined so as to shed light on the motion mechanisms, chemotactic behavior, and specific survival strategies of unicellular parasites. With these new tools in hand, we can elucidate the mechanisms of motility and force generation of unicellular parasites, and identify ways to manipulate and eventually inhibit them.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Biophysikalische Chemie (Pfohl)
UniBasel Contributors:Pfohl, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:1471-4922
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:09 Jan 2017 15:13
Deposited On:09 Jan 2017 15:13

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