edoc

Effects of Cerebellothalamic Tractotomy on Cognitive and Emotional Functioning in Essential Tremor: A Preliminary Study in 5 Essential Tremor Patients.

Ledermann, Katharina and Jeanmonod, Daniel and McAleese, Salome and Aufenberg, Christoph and Opwis, Klaus and Martin-Soelch, Chantal. (2015) Effects of Cerebellothalamic Tractotomy on Cognitive and Emotional Functioning in Essential Tremor: A Preliminary Study in 5 Essential Tremor Patients. Stereotactic and Functional Neurosurgery, 93 (2). pp. 127-132.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/51316/

Downloads: Statistics Overview

Abstract

BACKGROUND: Subthalamic stereotactic interventions have recently caught renewed interest as a treatment for essential tremor (ET). However, it is not clear whether these interventions are associated with neurocognitive, mood or personality changes.
OBJECTIVE: To investigate neurocognition, neuropsychiatric functions and personality variables in patients with ET and to explore the neurocognitive and neuropsychiatric effects of cerebellothalamic tractotomy (CTT), a form of subthalamotomy.
METHODS: In our study, we investigated cognitive functions, frontal functions, mood and personality variables in 5 patients with intractable ET. Patients were tested before and 3 months after surgery using neuropsychological tests, clinical scales for depression, anxiety, anger regulation and a personality test.
RESULTS: Before surgery, ET patients showed normal neurocognitive function, a slightly elevated frontal lobe score in the dimensions mental control and memory, without being indicative of a frontal lesion, and no elevated depression or anxiety scores compared to norm values. After surgery, there was no change in neurocognitive function and no increase in depression or anxiety scores.
CONCLUSION: In this exploratory study on 5 ET patients, CTT was not associated with alterations of mood or neurocognitive functions.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Persönlichkeits- und Entwicklungspsychologie > Allgemeine Psychologie und Methodologie (Opwis)
UniBasel Contributors:Opwis, Klaus
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Karger
ISSN:1011-6125
e-ISSN:1423-0372
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:24 Sep 2018 15:49
Deposited On:24 Sep 2018 15:49

Repository Staff Only: item control page