Circadian sleep-wake, well-being and light treatment in borderline personality disorder

Bromundt, V. and Wirz-Justice, A. and Kyburz, S. and Opwis, K. and Dammann, G. and Cajochen, C.. (2013) Circadian sleep-wake, well-being and light treatment in borderline personality disorder. Journal of Personality Disorders, 27 (5). pp. 680-696.

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Individuals with borderline personality disorder (BPD) frequently suffer from sleep disturbances. The authors investigated circadian rhythms, sleep, and well-being in women with BPD in their habitual life conditions during 3 weeks with morning light therapy (LT) and 3 weeks without LT (oLT). Sleep–wake cycles were measured using wrist actimetry, proximal skin temperature as an indirect index of relaxation, as well as weekly salivary melatonin to document the internal circadian rhythm phase. Questionnaires assessed clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment. Women with BPD had significantly worse subjective sleep quality and reduced daytime alertness compared to controls. Sleep–wake cycles in BPD ranged from highly disturbed to extremely regular patterns. Melatonin and proximal skin temperature profiles revealed appropriate synchronization of the circadian system with the sleep–wake cycle in most BPD women and in all controls. Morning LT significantly phase-advanced activity in BPD compared to oLT, shortened sleep duration, decreased movement time, and increased skin temperature during sleep (a marker of relaxation). Although general depression scores and borderline symptoms did not change, daytime alertness improved with morning LT, and atypical depression scores were attenuated. Morning LT is a potential adjunct treatment for BPD.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Persönlichkeits- und Entwicklungspsychologie > Allgemeine Psychologie und Methodologie (Opwis)
UniBasel Contributors:Opwis, Klaus
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Guilford Press
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:29 Jan 2018 10:13
Deposited On:29 Jan 2018 10:13

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