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Challenging the role of microtubules in Tobacco mosaic virus movement by drug treatments is disputable

Seemanpillai, Mark and Elamawi, Rabab and Ritzenthaler, Christophe and Heinlein, Manfred. (2006) Challenging the role of microtubules in Tobacco mosaic virus movement by drug treatments is disputable. Journal of Virology, 80 (13). pp. 6712-6715.

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Official URL: http://edoc.unibas.ch/45436/

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Abstract

The movement protein (MP) of Tobacco mosaic virus interacts with microtubules during infection. Although this interaction is correlated with the function of MP in the cell-to-cell transport of viral RNA, a direct role of microtubules in the movement process was recently challenged by studies involving the treatment of plants with inhibitors of microtubule polymerization. Here, we report evidence suggesting that such treatments may not efficiently disrupt all microtubules. Thus, results obtained from studies using microtubule inhibitors may have to remain open to interpretation with regard to the involvement of microtubules in viral RNA trafficking.
Faculties and Departments:05 Faculty of Science > Departement Umweltwissenschaften > Botanik
UniBasel Contributors:Heinlein, Manfred
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:American Society of Microbiology
ISSN:0022-538X
e-ISSN:1098-5514
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:13 Dec 2017 10:42
Deposited On:13 Dec 2017 10:42

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