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Long-term physical activity is associated with reduced arterial stiffness in older adults : longitudinal results of the SAPALDIA cohort study

Endes, Simon and Schaffner, Emmanuel and Caviezel, Seraina and Dratva, Julia and Autenrieth, Christine S. and Wanner, Miriam and Martin, Brian and Stolz, Daiana and Pons, Marco and Turk, Alexander and Bettschart, Robert and Schindler, Christian and Künzli, Nino and Probst-Hensch, Nicole and Schmidt-Trucksäss, Arno. (2016) Long-term physical activity is associated with reduced arterial stiffness in older adults : longitudinal results of the SAPALDIA cohort study. Age and ageing, 45 (1). pp. 110-115.

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Official URL: http://edoc.unibas.ch/41974/

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Abstract

longitudinal analyses of physical activity (PA) and arterial stiffness in populations of older adults are scarce. We examined associations between long-term change of PA and arterial stiffness in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA).; we assessed PA in SAPALDIA 2 (2001-03) and SAPALDIA 3 (2010-11) using a short questionnaire with a cut-off of at least 150 min of moderate-to-vigorous PA per week for sufficient activity. Arterial stiffness was measured oscillometrically by means of the brachial-ankle pulse wave velocity (baPWV) in SAPALDIA 3. We used multivariable mixed linear regression models adjusted for several potential confounders in 2,605 persons aged 50-81.; adjusted means of baPWV were significantly lower in persons with sufficient moderate-to-vigorous PA (i) in SAPALDIA 2 but not in SAPALDIA 3 (P = 0.048) and (ii) in both surveys (P = 0.001) compared with persons with insufficient activity in both surveys. There was a significant interaction between sex and the level of change in PA concerning baPWV (P = 0.03). The triples of parameter estimates describing the association between level of PA change and baPWV were not significantly different between the two sex-specific models (P = 0.07).; keeping up or adopting a physically active lifestyle was associated with lower arterial stiffness in older adults after a follow-up of almost a decade. Increasing the proportion of older adults adhering to PA recommendations incorporating also vigorous PA may have a considerable impact on vascular health at older age and may contribute to healthy ageing in general.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
UniBasel Contributors:Schaffner, Emmanuel and Dratva, Julia and Autenrieth, Christine and Schindler, Christian and Künzli, Nino and Probst Hensch, Nicole
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:1468-2834
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:30 Jun 2016 11:03
Deposited On:19 Apr 2016 12:20

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