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Synthesis of New Alkylated Mononucleotide Analogues and Their Repair Proficiency by the Prokaryotic DNA Repair Protein AlkB

Tishinov, Kiril and Gillingham, Dennis. (2015) Synthesis of New Alkylated Mononucleotide Analogues and Their Repair Proficiency by the Prokaryotic DNA Repair Protein AlkB. Synlett, 26 (19). pp. 2720-2723.

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Official URL: http://edoc.unibas.ch/41874/

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Abstract

We describe the synthesis of a variety of new alkylated mononucleotides and examine their repair proficiency with the prokaryotic direct DNA repair protein AlkB. A comparison of rates of repair among the different substrates supports the currently accepted radical mechanism.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Organische Chemie (Gillingham)
UniBasel Contributors:Gillingham, Dennis
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Georg Thieme Verlag
ISSN:0936-5214
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:17 Mar 2017 13:09
Deposited On:25 Apr 2016 09:46

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