Hiller, Sebastian and Wider, Gerhard and Imbach, Lukas L. and Wüthrich, Kurt. (2008) Interactions with hydrophobic clusters in the urea-unfolded membrane protein OmpX. Angewandte Chemie. International edition in English, 47 (5). pp. 977-981.
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Abstract
A denatured membrane protein in 8 M urea was characterized. Two hydrophobic clusters, separated by 50 amino acids in the polypeptide chain, are shown to bind independently to detergent micelles (see picture). Long-range interactions between the two clusters are not observed. These observations provide new insights into protein folding mechanisms.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Structural Biology & Biophysics > Structural Biology (Hiller) |
|---|---|
| UniBasel Contributors: | Hiller Odermatt, Sebastian |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | VCH |
| ISSN: | 1521-3773 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 13 Dec 2017 14:42 |
| Deposited On: | 17 Aug 2016 07:28 |
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