Inter-subject modelling of liver deformation during radiation therapy

Martin von Siebenthal, and Gabor Szekely, and Antony Lomax, and Philippe Cattin, . (2007) Inter-subject modelling of liver deformation during radiation therapy. In: Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 : 10th International Conference, Brisbane, Australia, October 29 - November 2, 2007 ; Proceedings, Part 1. Berlin, pp. 659-666.

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Official URL: http://edoc.unibas.ch/dok/A6308304

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This paper presents a statistical model of the liver deformation that occurs in addition to the quasi-periodic respiratory motion. Having an elastic but still compact model of this variability is an important step towards reliable targeting in radiation therapy. To build this model, the deformation of the liver at exhalation was determined for 12 volunteers over roughly one hour using 4DMRI and subsequent non-rigid registration. The correspondence between subjects was established based on mechanically relevant landmarks on the liver surface. Leave-one-out experiments were performed to evaluate the accuracy in predicting the liver deformation from partial information, such as a point tracked by ultrasound imaging. Already predictions from a single point strongly reduced the localisation errors, whilst the method is robust with respect to the exact choice of the measured predictor.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Imaging and Computational Modelling > Center for medical Image Analysis & Navigation (Cattin)
UniBasel Contributors:Cattin, Philippe Claude
Item Type:Conference or Workshop Item, refereed
Conference or workshop item Subtype:Conference Paper
Note:Also published in: Lecture notes in computer science. - Berlin : Springer. - 4791 (2007), S. 659-666 -- Publication type according to Uni Basel Research Database: Conference paper
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Last Modified:03 Jul 2015 08:53
Deposited On:03 Jul 2015 08:53

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