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Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy

Sabarth, N. and Hurwitz, R. and Meyer, T. F. and Bumann, D.. (2002) Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy. Infection and Immunity, 70 (11). pp. 6499-6503.

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Official URL: http://edoc.unibas.ch/dok/A5259823

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Abstract

A multiparameter selection of Helicobacter pylori antigens for vaccine development identified 15 candidates, 6 of which are known protective antigens. Two novel antigens with low homology to other organisms (HP0231 and HP0410) were overexpressed and purified with high yields. Both confer protective immunity in the mouse Helicobacter infection model.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Molecular Microbiology (Bumann)
UniBasel Contributors:Bumann, Dirk
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:American Society for Microbiology
ISSN:0019-9567
e-ISSN:1098-5522
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:27 Nov 2017 09:19
Deposited On:22 Mar 2012 13:23

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