Pain and placebo in pediatrics : comprehensive review of laboratory and clinical findings

Simmons, Kanesha and Ortiz, Robin and Kossowsky, Joe and Krummenacher, Peter and Grillon, Christian and Pine, Daniel and Colloca, Luana. (2014) Pain and placebo in pediatrics : comprehensive review of laboratory and clinical findings. Pain, Vol. 155, H. 11. pp. 2229-2235.

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Official URL: http://edoc.unibas.ch/dok/A6337633

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Pain modulation by placebo mechanisms is one of the most robust and best-studied phenomena, yet almost all research investigating the mechanisms and implications of the placebo analgesia are based on adult research. After highlighting crucial aspects that need to be considered in studying pain modulation in children, this comprehensive review examines studies related to pain modulation with an emphasis on factors such as age, neural development and pain measures. We critically discuss psychological mechanisms underlying placebo effects, including (1) verbally induced expectations, (2) conditioning and learning mechanisms, and (3) child-parent-physician interactions. Taken together, research suggests that placebo mechanisms can affect therapeutic outcomes and potentially be exploited clinically to improve clinical outcomes in pediatric population. Recommendations for further investigating the mechanistic bases and harnessing placebo effects for supportive therapeutic applications are given.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Ehemalige Einheiten Psychologie > Clinical Child and Adolescent Psychology (Schneider)
07 Faculty of Psychology > Departement Psychologie > Health & Intervention > Klinische Psychologie und Psychotherapie (Gaab)
UniBasel Contributors:Kossowsky, Joe
Item Type:Article, refereed
Article Subtype:Book Review
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:08 May 2015 08:44
Deposited On:08 May 2015 08:44

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