edoc

Simple semi-automated portable capillary electrophoresis instrument with contactless conductivity detection for the determination of beta-agonists in pharmaceutical and pig-feed samples

Nguyen, T. A. H. and Pham, T. N. M. and Doan, T. T. and Ta, T. T. and Saiz, J. and Nguyen, T. Q. H. and Hauser, P. C. and Mai, T. D.. (2014) Simple semi-automated portable capillary electrophoresis instrument with contactless conductivity detection for the determination of beta-agonists in pharmaceutical and pig-feed samples. Journal of chromatography A, Vol. 1360. pp. 305-311.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A6337835

Downloads: Statistics Overview

Abstract

An inexpensive, robust and easy to use portable capillary electrophoresis instrument with miniaturized high-voltage capacitively coupled contactless conductivity detection was developed. The system utilizes pneumatic operation to manipulate the solutions for all flushing steps. The different operations, i.e. capillary flushing, interface rinsing, and electrophoretic separation, are easily activated by turning an electronic switch. To allow the analysis of samples with limited available volume, and to render the construction less complicated compared to a computer-controlled counterpart, sample injection is carried out hydrodynamically directly from the sample vial into the capillary by manual syphoning. The system is a well performing solution where the financial means for the highly expensive commercial instruments are not available and where the in-house construction of a sophisticated automated instrument is not possible due to limited mechanical and electronic workshop facilities and software programming expertise. For demonstration, the system was employed successfully for the determination of some beta-agonists, namely salbutamol, metoprolol and ractopamine down to 0.7 ppm in pharmaceutical and pig-feed sample matrices in Vietnam. (C) 2014 Elsevier B.V. All rights reserved.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Analytische Chemie (Hauser)
UniBasel Contributors:Hauser, Peter C. P. C.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0021-9673
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:06 Mar 2015 07:44
Deposited On:06 Mar 2015 07:44

Repository Staff Only: item control page